Understanding Your Pain

How Pain Treatment Works

Once you understand the mechanisms of pain, the purpose of each treatment becomes clear.

Treatment What It Does Which Type of Pain?
Anti-inflammatory drugs (NSAIDs) Reduce inflammation and decrease pain signals Mainly nociceptive pain
Nerve medications (e.g., pregabalin) Calm abnormal nerve excitability Neuropathic pain
Descending inhibition boosters (e.g., duloxetine) Strengthen the brain's pain-suppression pathway to the spinal cord Chronic pain, neuropathic pain
Nerve block injections Temporarily stop signals in a specific nerve Both types
Surgery (decompression) Physically remove the pressure on the nerve Pain caused by compression
Spinal cord stimulation (SCS) Deliver electrical stimulation to the spinal cord, making it harder for pain signals to reach the brain Neuropathic pain, chronic pain

Each treatment works at a different point along the pain pathway.