When Pain Medication Stops Working

What Comes After Medication

The Step-Up Approach

When medication alone isn't enough, these options are available:

Nerve Block Injections

Injections are often the next step after medication:

Type What it does How long it lasts
Epidural block Reduces inflammation inside the spinal canal Days to weeks
Nerve root block Targets the specific compressed nerve directly Days to months
Caudal block Delivers medication through the base of the spine Days to weeks

Nerve block injections serve a dual purpose: treatment and diagnosis. If an injection brings relief, it confirms which nerve is the source of the problem — which helps guide future treatment decisions.

[!info] Learn more Nerve Block Injections explains the types, effectiveness, and limitations in detail.

Surgery

When conservative treatment and injections aren't providing adequate relief, surgery may be considered:

Surgery type Best for Key feature
Decompression Stenosis at a clearly identified location Relatively low physical burden
Fusion Spinal instability or multi-level stenosis Higher physical burden

[!info] Learn more Surgery covers the types of surgery and their risks.

SCS (Spinal Cord Stimulation)

For people who feel "medication isn't enough" but "major surgery feels like too much", SCS is an important option to consider.

SCS feature What it means for you
Low physical burden Can be performed under local anesthesia
Trial period available Test it for one week before committing
Reversible The device can be removed if it doesn't help
May reduce medication needs If SCS controls the pain, your medication dose may be lowered

SCS is especially worth considering when:

  • Conservative treatment (medication, injections) hasn't provided enough relief
  • Neuropathic pain is the primary issue — and surgery is unlikely to address it
  • Multi-level fusion would be needed, but the physical burden is a concern
  • Pain persists even after previous surgery

[!info] Learn more Spinal Cord Stimulation (SCS) explains how it works and who it's suited for.